Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
High Performance Polymers
This Article
Right arrow Full Text (OnlineFirst PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Qun, X. L.
Right arrow Articles by F, Z. M
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Article

Antibacterial Nanofibers of Self-quaternized Block Copolymers of 4-Vinyl Pyridine and Pentachlorophenyl Acrylate

Xu Li Qun1, Yao Fang1, Yin Shan1, Fu Guo-Dong1*, Shen Liang2, Nie S Z3, and Zhu M F4

1 Southeast University
2 Jiangxi Science & Technology Normal University
3 Suzhou Institute of Sichuan University
4 Donghua University

* To whom correspondence should be addressed. E-mail: fu7352{at}seu.edu.cn.


  Abstract

Well-defined antibacterial block copolymers of 4-vinyl pyridine (4VP) and pentachlorophenyl acrylate (PCPA) (P(4VP-b-PCPA)) were prepared via reversible addition–fragmentation chain transfer (RAFT) polymerization. Electrospinning of the P(4VP-b-PCPA) from a solution in mixed tetrahydrofuran and dimethylformamide gave rise to fibers with diameters in the range of 0.5–4.0 µm. The quaternary ammonium salts (QASs) were generated by N-alkylation of pyridine groups of P4VP block and chloro-aromatic compounds of PPCPA block (or self-quaternization of P(4VP-b-PCPA)). The self-quaternization of P(4VP-b-PCPA) nanofibers was studied by X-ray photoelectron spectroscopy. Attributable to the hydrophobicity of the PPCPA blocks and the electrostatic interaction of QASs generated from the self-quaternization of P(4VP-b-PCPA), the resulting nanofibers exhibit a high antibacterial efficiency. The antibacterial effect of the P(4VP-b-PCPA) nanofibers was assayed using Escherichia coli and Staphylococcus aureus cultures. It was found that 99.6% of E. coli and 99.1% S. aureus were killed after being in contact with 50 mg nanofibers in 10 min. The permanence of antibacterial activity of the self-quaternized P(4VP-b-PCPA) nanofibers was also demonstrated in repeat application.

First published on June 1, 2009
High Performance Polymers 2009, doi:10.1177/0954008309104776
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?